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Specialty Compounds RTP Company
Cabot CAB-O-SIL® M-5P Fumed Silica
Categories: Other Engineering Material

Material Notes: Product highlights: CAB-O-SIL M-5P fumed silica is an excipient of extremely high purity that is suitable for use as a multi-functional additive in the pharmaceutical industry. CAB-O-SIL M-5P fumed silica is compatible with many pharmaceutical ingredients and can act as a flow aid to reduce common issues in tablet and capsule production including poor flow through the hopper, active/inactive ingredient segregation, and tablet breakage during compaction.

Performance features:
Flow aid: CAB-O-SIL M-5P fumed silica’s glidant and anti-static properties can reduce the friction and static charges in high speed tablet and capsule machines. The addition of CAB-O-SIL M-5P fumed silica can enable better spacing between the powder particles, reduce moisture bridging and reduce static charge, helping to improve flow and prevent bridging in the hopper.
Die filling aid: CAB-O-SIL M-5P fumed silica can improve the flow properties of the mixture and aid particle rearrangement within the die during the early stages of die filling and compression, promoting uniform tablet weight and active ingredient content.
Compaction aid: CAB-O-SIL M-5P fumed silica can also increase tablet hardness/strength by facilitating particle flow and rearrangement during the early stages of the compression process, which can increase the bonding strength between powder particles. This can help prevent subsequent tablet defects like chipping, capping, lamination and breaking.

Information provided by Cabot Corporation

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