Hyaluronic acid (HA) also called hyaluronan, hyaluronate is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans in that it is nonsulfated, forms in the plasma membrane instead of the Golgi, and can be very large, with its molecular weight often reaching the millions. One of the chief components of the extracellular matrix, hyaluronan contributes significantly to cell proliferation and migration, and may also be involved in the progression of some malignant tumors.
Assay (glucuronic acid): min. 46%
Nitrogen: max. 4%
Loss on drying: max. 8%
Protein: max. 0.03%
Heavy metals (as Pb): <20 ppm
residue on ignition (SO4-ash): max. 17.5% Application: Hyaluronic acid, an anionic, nonsulfated glycosaminoglycan (GAG), may be used in research involving processes such as inflammation, cell signaling, cell migration, cell differentiation, tissue engineering and wound-healing. Hyaluronic acid may be used as a substrate to identify and characterized catabolizing enzymes such as hyaluronidase(s). Hyaluronic acid may be used in biomaterials research for the development of biological scaffolds for wound-healing applications and hyaluronic acid fillers in human skin. Morphology: White powder |
Synonyms: HA, Hyaluronan, Hyaluronate, Sodium hyaluronate, Poly(b-glucuronic acid-[1?3]-b-N-acetylglucosamine-[1?4]); a-?UA-(1?34)-GlcNAc; sodium hyaluronate powder, hyaluronic acid; hyalobarrier gel; haluronic acid; hyaluronic acid sodium; hyaluronic acid na-salt; |