| EUDRAGIT FS 30 D, the milky-white liquid of low viscosity with a faint characteristic odor is the aqueous dispersion of an anionic copolymer based on methyl acrylate, methyl methacrylate and methacrylic acid. It is insoluble in acidic media, but dissolves by salt formation above pH 7.0. Apart from its enteric properties, its dissolution at a higher pH value allows targeted colon delivery. With a glass transition temperature of 48°C, EUDRAGIT FS 30 D is a very flexible polymer. Due to the low minimum film forming temperature only small amounts of plasticizer are required to get a smooth film formation. Physical properties: It is a milky-white liquid of low viscosity with a faint characteristic odor. Characteristics: - A solubility above pH 7.0 allows specific colon targeting
- Because of its flexibility it is particularly suitable for multi unit dosage forms
- Matrix systems with EUDRAGIT FS 30 D will release 100% of the drug
- Polymer amounts of 10 to 20 % are sufficient to get a pH-independent matrix
- The flexibility of EUDRAGIT FS 30 D makes this polymer particularly suitable for the mixing with EUDRAGIT L 30 D-55
- Amounts below 50 % do only influence the flexibility of the EUDRAGIT L 30 D-55 coating, not the release profile. With amounts > 75 % specific sites in the GI tract can be targeted.
CAS number: 26936 – 24 – 3Chemical/ IUPAC name: Poly(methyl acrylate-co-methyl methacrylate-co-methacrylic acid) 7:3:1 INCI name: Acrylates Copolymer Information provided by Evonik |
